Publications | Mysite

Detection of DNA Breaks in Dividing Human Cells by Neutral Comet Assay

Anthony Nelligan and Huzefa Dungrawala

J Vis Exp. 2024 Aug 23;(210). doi: 10.3791/67110.

PubMed

Article

Replication fork stalling in late S-phase elicits nascent strand degradation by DNA mismatch repair

Erica Colicino-Murbach, Caitlin Hathaway and Huzefa Dungrawala

Nucleic Acids Research, 2024 Aug 24:gkae721. doi: 10.1093/nar/gkae721

PubMed

Article

DCAF14 regulates CDT2 to promote SET8-dependent replication fork protection

Neysha Tirado-Class, Caitlin Hathaway, Anthony Nelligan, Thuan Nguyen, Huzefa Dungrawala

Life Science Alliance 2023 Nov 8;7(1):e202302230. doi: 10.26508/lsa.202302230.

PubMed

Article

OTUD5 limits replication fork instability by organizing chromatin remodelers

de Vivo A, Song H, Lee Y, Tirado-Class N, Sanchez A, Westerheide S, Dungrawala H, Kee Y.

Nucleic Acids Res. 2023 Sep 15:gkad732. doi: 10.1093/nar/gkad732.

PubMed

Article

PHIP variants associated with Chung-Jansen syndrome disrupt replication fork stability and genome integrity

Neysha Tirado-Class, Caitlin Hathaway, Wendy K. Chung and Huzefa Dungrawala

Cold Spring Harbor Molecular Case Studies 2022 Jul 21

PubMed

Article

DCAF14 promotes stalled fork stability to maintain genome integrity

Arik Townsend, Gabriella Lora, Justin Engel, Neysha Tirado-Class, Huzefa Dungrawala

Cell Rep 2021 Jan 26;34(4):108669. doi: 10.1016/j.celrep.2020.108669.

PubMed

Article

Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

Wessel SR, Mohni KN, Luzwick JW, Dungrawala H, Cortez D

Cell Rep. 2019 Sep 24;28(13):3497-3509.e4. doi: 10.1016/j.celrep.2019.08.051

PubMed

Article

RADX Modulates RAD51 Activity to Control Replication Fork Protection.

Bhat KP, Krishnamoorthy A, Dungrawala H, Garcin EB, Modesti M, Cortez D.

Cell Rep. 2018 Jul 17;24(3):538-545. doi: 10.1016/j.celrep.2018.06.061.

PubMed

Article

Yeast lifespan variation correlates with cell growth and SIR2 expression.

Smith JT, White JW, Dungrawala H, Hua H, Schneider BL.

PLoS One. 2018 Jul 6;13(7):e0200275. doi: 10.1371/journal.pone.0200275. eCollection 2018.

PubMed

Article

RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.

Dungrawala H, Bhat KP, Le Meur R, Chazin WJ, Ding X, Sharan SK, Wessel SR, Sathe AA, Zhao R, Cortez D.

Mol Cell. 2017 Aug 3;67(3):374-386.e5. doi: 10.1016/j.molcel.2017.06.023. Epub 2017 Jul 20.

PubMed

Article

Synchronization of Yeast.

Smith J, Manukyan A, Hua H, Dungrawala H, Schneider BL.

Methods Mol Biol. 2017;1524:215-242.

PubMed

Article

ETAA1 acts at stalled replication forks to maintain genome integrity.

Bass TE, Luzwick JW, Kavanaugh G, Carroll C, Dungrawala H, Glick GG, Feldkamp MD, Putney R, Chazin WJ, Cortez D.

Nat Cell Biol. 2016 Nov;18(11):1185-1195. doi: 10.1038/ncb3415. Epub 2016 Oct 10.

PubMed

Article

The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.

Dungrawala H, Rose KL, Bhat KP, Mohni KN, Glick GG, Couch FB, Cortez D.

Mol Cell. 2015 Sep 17;59(6):998-1010. doi: 10.1016/j.molcel.2015.07.030. Epub 2015 Sep 10.

PubMed

Article

Purification of proteins on newly synthesized DNA using iPOND.

Dungrawala H, Cortez D.

Methods Mol Biol. 2015;1228:123-31. doi: 10.1007/978-1-4939-1680-1_10.

PubMed

Article

Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry.

Sirbu BM, McDonald WH, Dungrawala H, Badu-Nkansah A, Kavanaugh GM, Chen Y, Tabb DL, Cortez D

J Biol Chem. 2013 Nov 1;288(44):31458-67. doi: 10.1074/jbc.M113.511337. Epub 2013 Sep 18.

PubMed

Article

Identification of new cell size control genes in S. cerevisiae.

Dungrawala H, Hua H, Wright J, Abraham L, Kasemsri T, McDowell A, Stilwell J, Schneider BL.

Cell Div. 2012 Dec 12;7(1):24. doi: 10.1186/1747-1028-7-24.

PubMed

Article

A growing role for hypertrophy in senescence.

Wright J, Dungrawala H, Bright RK, Schneider BL.

FEMS Yeast Res. 2013 Feb;13(1):2-6. doi: 10.1111/1567-1364.12015. Epub 2012 Nov 23.

PubMed

Article

FASTA barcodes: a simple method for the identification of yeast ORF deletions.

McMahon KW, Manukyan A, Dungrawala H, Montgomery M, Nordstrom B, Wright J, Abraham L, Schneider BL.

Yeast. 2011 Sep;28(9):661-71. doi: 10.1002/yea.1894. Epub 2011 Aug 1.

PubMed

Article

Synchronization of yeast.

Manukyan A, Abraham L, Dungrawala H, Schneider BL.

Methods Mol Biol. 2011;761:173-200. doi: 10.1007/978-1-61779-182-6_12.

PubMed

Article

Cell size and growth rate are major determinants of replicative lifespan.

Yang J, Dungrawala H, Hua H, Manukyan A, Abraham L, Lane W, Mead H, Wright J, Schneider BL.

Cell Cycle. 2011 Jan 1;10(1):144-55. doi: 10.4161/cc.10.1.14455.

PubMed

Article